Table 3.
Unadjusted and adjusted independent associations between participant characteristics and correct risk recall in bivariate and multivariate analyses
| APOE genotype | Number of APOE risk-increasing alleles | Alzheimer's disease lifetime risk (± 5 percentage points) | Alzheimer's disease lifetime risk (exact) | |||||
|---|---|---|---|---|---|---|---|---|
| Unadjusted OR (95% CI) | Adjusted OR (95% CI) | Unadjusted OR (95% CI) | Adjusted OR (95% CI) | Unadjusted OR (95% CI) | Adjusted OR (95% CI) | Unadjusted OR (95% CI) | Unadjusted OR (95% CI) | |
| Age | 0.99 (0.97-1.01) | 0.99 (0.98-1.02) | 0.96 (0.93-0.99)* | 0.97 (0.94-1.01) | 0.96 (0.94-0.99)* | 0.96 (0.93-1.00)* | 0.98 (0.96-1.00)* | 0.98 (0.96-1.00)* |
| Male (ref: female) | 1.10 (0.62-1.96) | 0.77 (0.40-1.49) | 1.04 (0.53-2.04) | 0.48 (0.19-1.19) | 1.05 (0.53-2.08) | 0.76 (0.34-1.68) | 1.35 (0.82-2.23) | 1.35 (0.82-2.23) |
| Years of education | 1.16 (1.03-1.31)* | 1.03 (0.90-1.19) | 1.53 (1.30-1.80)** | 1.39 (1.16-1.68)** | 1.28 (1.10-1.48)* | 1.17 (0.98-1.39) | 1.01 (0.91-1.12) | 1.01 (0.91-1.12) |
| African American or other (ref: European-American) | 0.40 (0.20-0.81)* | 0.55 (0.25-1.21) | 0.33 (0.15-0.71)* | 0.49 (0.18-1.31) | 0.42 (0.19-0.92)* | 0.39 (0.15-1.02) | 1.06 (0.54-2.09) | 1.06 (0.54-2.09) |
| Family history | 1.29 (1.03-1.61)* | 1.23 (0.98-1.54) | 1.52 (1.13-2.04)* | 1.44 (1.04-1.98)* | 1.04 (0.82-1.31) | 0.94 (0.75-1.18) | 1.08 (0.92-1.27) | 1.08 (0.92-1.27) |
| Higher numeracy (ref: lower numeracy) | 2.10 (1.17-3.77)* | 1.65 (0.83-3.30) | 3.97 (1.96-8.08)** | 2.79 (1.12-6.93)* | 2.14 (1.06-4.35)* | 1.20 (0.50-2.86) | 1.50 (0.89-2.53) | 1.50 (0.89-2.53) |
| Self-reported comfort with numbers† | 1.56 (1.16-2.09)* | 1.37 (0.98-1.93) | 2.18 (1.53-3.10)** | 1.41 (0.92-2.16) | 1.42 (1.01-2.00)* | 1.08 (0.72-1.62) | 1.22 (0.94-1.57) | 1.22 (0.94-1.57) |
*
p<0.05
**
p<0.001
†
Per one-unit increase