Table 2.
Demographic model | Sample size n | ρ | Nominal level
|
Sample size n | ρ | Nominal level
|
||||
---|---|---|---|---|---|---|---|---|---|---|
α=0.05 | α=0.01 | α=0.001 | α=0.05 | α=0.01 | α=0.001 | |||||
| ||||||||||
Population structure | 100 | 1.5 | 0.0388 | 0.0116 | 0.0016 | 60 | 1.5 | 0.0468 | 0.0116 | 0.0016 |
3 | 0.0316 | 0.0056 | 0.0008 | 3 | 0.0324 | 0.0084 | 0.0012 | |||
6 | 0.0244 | 0.0045 | 0.0000 | 6 | 0.0232 | 0.0044 | 0.0004 | |||
9 | 0.0164 | 0.0028 | 0.0000 | 9 | 0.0228 | 0.0052 | 0.0004 | |||
| ||||||||||
Population expansion | 100 | 1.5 | 0.0432 | 0.0080 | 0.0008 | 60 | 1.5 | 0.0352 | 0.0056 | 0.0012 |
3 | 0.0352 | 0.0052 | 0.0008 | 3 | 0.0264 | 0.0064 | 0.0012 | |||
6 | 0.0252 | 0.0036 | 0.0004 | 6 | 0.0224 | 0.0048 | 0.0008 | |||
9 | 0.0228 | 0.0052 | 0.0008 | 9 | 0.0148 | 0.0024 | 0.0000 | |||
| ||||||||||
Population bottleneck 150/300 |
100 | 1.5 | 0.0768 | 0.0184 | 0.0028 | 60 | 1.5 | 0.0732 | 0.0236 | 0.0056 |
3 | 0.0420 | 0.0092 | 0.0012 | 3 | 0.0500 | 0.0116 | 0.0012 | |||
6 | 0.0296 | 0.0052 | 0.0008 | 6 | 0.0324 | 0.0080 | 0.0012 | |||
9 | 0.0264 | 0.0032 | 0.0004 | 9 | 0.0240 | 0.0048 | 0.0004 | |||
| ||||||||||
Population bottleneck 250/500 |
100 | 1.5 | 0.0692 | 0.0192 | 0.0028 | 60 | 1.5 | 0.0724 | 0.0184 | 0.0024 |
3 | 0.0380 | 0.0068 | 0.0008 | 3 | 0.0404 | 0.0084 | 0.0012 | |||
6 | 0.0340 | 0.0064 | 0.0008 | 6 | 0.0336 | 0.0056 | 0.0004 | |||
9 | 0.0272 | 0.0028 | 0.0004 | 9 | 0.0292 | 0.0076 | 0.0004 |
All results were based on 2,500 simulations using software ms [10], and a genomic region of 101 SNPs was simulated