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. Author manuscript; available in PMC: 2015 Jun 17.
Published in final edited form as: Org Lett. 2008 Apr 26;10(11):2135–2138. doi: 10.1021/ol800532p

Table 2.

Cross-Coupling of 2a and 4-Bromobenzonitrile with Diverse Ligandsa

graphic file with name nihms694691u3.jpg
entry ligand abbreviation ligand loading (%) isolated yield (%)
1 graphic file with name nihms694691t22.jpg RuPhos 6 76
2 graphic file with name nihms694691t23.jpg SPhos 6 58
3 graphic file with name nihms694691t24.jpg [(S)-BINAP] 3 76
4 graphic file with name nihms694691t25.jpg DPEPhos 3 68
5 graphic file with name nihms694691t26.jpg FcP(i-Pr)2 3 73
a

All reactions were carried out using 0.5 mmol of 4-bromobenzonitrile and 0.55 mmol of 2a.