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. Author manuscript; available in PMC: 2016 Apr 1.
Published in final edited form as: Lancet Oncol. 2015 Apr;16(4):e165–e172. doi: 10.1016/S1470-2045(14)71180-5

Figure 1. Alveolar type II cells could be a common precursor that can give rise to both adenocarcinoma and small-cell lung cancer (SCLC).

Figure 1

Diagram depicts the cells of origin of adenocarcinoma and SCLC. Neuroendocrine cells and possibly alveolar type II cells can give rise to SCLC (left and centre), whereas clara cells and alveolar type II cells can give rise to adenocarcinoma (right and centre).