Table 2.
Outcomes according to the initial ventilation strategy (unadjusted outcomes)
| Initial NIV N = 974 (27.7%) |
Initial IMV N = 1603 (45.5%) |
NIV failure N = 89 of 974 |
P-value comparing Initial NIV vs Initial IMV | |
|---|---|---|---|---|
| ICU mortality | 30 (3.1%) | 168 (10.5%) | 12 (13.5%) | <0.001 |
| Hospital mortality | 72 (7.4%) | 258 (16.1%) | 20 (22.5%) | <0.001 |
| ICU LOS | 2.1 [1.3, 3.5] | 4.2 [2.5, 7.9] | 7.0 [4.7, 11.8] | <0.001 |
| Hospital LOS | 6.7 [4.3, 10.4] | 9.0 [5.6, 15.1] | 11.9 [7.9, 17.8] | <0.001 |
| Duration of IMV | ||||
| Median [25th, 75th] | N/A | 2.2 [1.1, 4.5] | 3.7 [1.7, 7.4] | N/A |
| < 3 Days on IMV | N/A | 1002 (62.5%) | 40 (44.9%) | N/A |
| 7 or More Days on IMV | N/A | 225 (14.0%) | 26 (29.2%) | N/A |
| Readmission to ICU | 53 (5.4%) | 126 (7.9%) | 6 (6.7%) | 0.019 |
| Discharge from Hospital for Survivors | ||||
| Other Hospital | 27 (3.0%) | 64 (4.8%) | 5 (7.3%) | <0.001 |
| Home | 537 (59.5%) | 714 (53.1%) | 29 (42.0%) | |
| Nursing Home/ Long-term acute care | 241 (26.7%) | 419 (31.2%) | 28 (40.6%) | |
| Other | 30 (3.3%) | 86 (6.4%) | 5 (7.3%) | |
| Hospice | 67 (7.4%) | 62 (4.6%) | 2 (2.9%) |
Data are given as N (sample Size) and Percent or Median [25th percentile, 75th Percentile]