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. Author manuscript; available in PMC: 2016 Jul 1.
Published in final edited form as: Crit Care Med. 2015 Jul;43(7):1386–1394. doi: 10.1097/CCM.0000000000000945

Table 4.

Predictors of NIV Failure in Initial NIV Patients

Variable RR; 95% CI
N = 649		 P-value Sensitivity Analysis
RR; 95% CI
N = 596		 Sensitivity Analysis
P-value
Age 65 or older 0.77; (0.47, 1.26) 0.291 0.96; (0.39,2.32) 0.922
SAPS II Score per unit 1.04; (1.03, 1.04) <0.001 1.03; (1.01, 1.05) 0.001
Cancer 2.29; (0.96, 5.45) 0.061 4.18; (1.67, 10.44) 0.002
Diabetes 0.64; (0.42, 0.97) 0.037 0.57; (0.37, 0.90) 0.015
*

Outcome variable: NIV Failure vs NIV. In the primary analysis, we assume that all patients with IMV after NIV are failures, even if their DNR code status is unknown. In the Sensitivity Analysis, we only look at patients with known “full code” (no code restriction) status.