Skip to main content
. Author manuscript; available in PMC: 2016 Jun 15.
Published in final edited form as: Cancer Res. 2015 Apr 21;75(12):2501–2509. doi: 10.1158/0008-5472.CAN-14-3361

Figure 2. Immunohistochemical (IHC) analysis of B7-H3 expression in human breast tissues.

Figure 2

Photomicrographs show representative staining results from normal breast tissues, various benign and precursor breast pathologies, as well as different types of breast cancer obtained from women undergoing biopsy or surgical resection. Graph summarizes composite IHC scores on B7-H3-stained tissues from normal tissue, benign and precursor lesions versus breast cancer. *P<0.001; error bars = standard deviations, Scale bar = 100 μm. ADH=Atypical ductal hyperplasia; ALH=Atypical lobular hyperplasia; ApoM=Apocrine metaplasia; CCL=Columnar cell lesion; DCIS=Ductal carcinoma in situ; FA=Fibroadenoma; FEA=Flat epithelial atypia; NPFCC=Non-proliferative fibrocystic changes; UDH=Usual ductal hyperplasia; Her2=Human epidermal growth factor receptor type 2 positive cancer; Luminal A=estrogen receptor and/or progesterone receptor positive cancer; Luminal B=estrogen receptor and/or progesterone receptor positive and Her2 positive cancer; Triple negative=estrogen, progesterone and Her2 negative cancer.