Table 1.
Woodchuckb | Strainb | Time post-infection, weeks | |||
---|---|---|---|---|---|
week 0 | week +6 | week +13 | week +14 | ||
F6693 | WHV7 | 0.0% (0/1500) | 75.0% (1192/1590) | 31.8% (652/2049) | 38.1% (720/1889) |
F6671 | WHV7 | 0.0% (0/1500) | 0.3% (5/1801) | 0.0% (0/1500) | 0.0% (0/1500) |
F6678 | WHVNY | 0.0% (0/1500) | 1.0% (17/1675) | 48.9% (1414/2894) | 22.4% (539/2411) |
M6543 | WHVNY | 0.0% (0/1500) | 70.7% (1840/2602) | 10.8% (367/3402) | 49.2%(1315/2672) |
F6541 | WHVNY | 0.0% (0/1500) | 66.0% (1221/1849) | 30.2% (768/2539) | 41.7% (800/1920) |
Staining of liver tissue samples for WHV core antigen was done as described previously (Freitas et al., 2012).
Woodchucks used in the current study, the strains of WHV used for infection, and harvesting of liver tissue samples for analysis are described in Materials and Methods.