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RT-PCR analysis of gene expression identified 22 genes that are preferentially expressed in CTCL, but not in normal skin from healthy volunteers or benign inflammatory dermatoses that often masquerade as CTCL (e.g., psoriasis, chronic eczema and pityriasis rubra pilaris or PRP). Notably, 17 of the above genes are upregulated in cluster 1 and 3 patients and potentially can serve as diagnostic and prognostic markers at the same time.
