Figure 2.
YAP and TAZ expression in OSCCs. One-way ANOVA analysis showing (A) YAP or (B) TAZ expression with respect to TCGA OSCC tumor grade or stage data. A pairwise t-test analysis comparing datasets revealed no significant expression changes. (C) Protein was extracted from poorly and moderately differentiated tumors, and associated adjacent epithelium (AE), and examined for YAP and pS127-YAP levels by immunoblotting. A representative image of our results is shown. Ponceau-S staining of the proteins on the immunoblotted membrane is shown as a loading control. Quantitation of the relative phospho-S127-YAP to total YAP is also shown.