Table 3. Risk of major adverse cardiovascular events among diabetic patients with advanced chronic kidney disease comparing TZD users vs. nonusers.

	No. of Events		Incidence Rate per 100 Patient-years		Crude HR (95% CI)	Adjusted HR + (95% CI)	PSM HR (95% CI)
TZD nonuser	580	934	2.2	3.7	1 (Ref.)	1 (Ref.)	1 (Ref.)
(n = 11,126)
TZD user	70	120	2.2	3.9	1.06 (0.87–1.28)	1.02 (0.84–1.24)	1.02 (0.83–1.26)
(n = 1,224)

Abbreviations: CI, confidence interval; HR, hazard ratio; PSM, propensity score matched; TZD, thiazolidinedione.

⁺A multivariate analysis was adjusted for all variables listed in Table 1.