Table 2.

Adherence to instructions-for-use for NAI and NXN

NAI instructions	NXN instructionsa
(1) Remove from outer case	(1) Remove medication and atomizer
(2) Pull off red safety guard	(2) Pull off both yellow caps from syringe
(3) Place black end onto patient’s outer thigh	(3) Pull off purple naloxone cap from naloxone cartridge
(4) Press firmly to activate	(4) Attach atomizer onto syringe by the hold wings on the atomizer
(5) Hold for at least 5 s	(5) Screw naloxone cartridge into syringe
	(6) Place atomizer tip into patient’s nostril
	(7) Push cartridge to administer some naloxone into one nostril
	(8) Push cartridge to administer approximately 1 mL naloxone into the other nostril

NAI naloxone 0.4 mg auto-injector, NXN naloxone nasal atomization kit

^aParticipants can perform steps 2–3 and 4–5 out of sequence