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. 2015 Apr 25;4(1):89–105. doi: 10.1007/s40122-015-0035-9

Table 5.

Critical use errors for NAI and NXN

Summary Phase 1 Phase 3
Total participants (n) 42 42
NAI task completion
 Remove from outer case 42 (100.0%) 42 (100.0%)
 Pull off red safety guard 42 (100.0%) 42 (100.0%)
 Place black end against muscle 41 (97.6%) 42 (100.0%)
 Press firmly to activate 42 (100.0%) 42 (100.0%)
 Hold for at least 1 s 39 (92.9%) 42 (100.0%)
NXN task completion
 Remove yellow caps from syringe 40 (95.2%) 42 (100.0%)
 Remove purple cap from the naloxone cartridge 42 (100.0%) 42 (100.0%)
 Attach atomizer to the syringe 15 (35.7%) 39 (92.9%)
 Twist or screw naloxone cartridge into syringe 35 (83.3%) 38 (90.5%)
 No drug leak during assembly 10 (23.8%) 33 (78.6%)
 Push cartridge to administer naloxone 7 (16.7%) 34 (81.0%)
 Push remaining cartridge into other nostril 0 (0.0%) 27 (64.3%)

NAI naloxone 0.4 mg auto-injector, NXN naloxone nasal atomization kit