Table 8.

Time to task completion for NAI and NXN

Summary	Phase 1	Phase 3	Comparison of NAI or NXN between phasesb
Total participants (n)	42	42
NAI total time to complete critical tasks (min)a
N	42	42	<0.0001
Mean (SD)	0.9 (0.25)	0.5 (0.15)
Median	0.9	0.5
Min, Max	0.5, 1.5	0.3, 0.9
NXN total time to complete critical tasks (min)a
N	42	42	<0.0001
Mean (SD)	6.0 (4.76)	2.0 (2.15)
Median	3.6	1.6
Min, Max	1.8, 15.0	0.8, 15.0
Comparison of NAI and NXN within each phaseb	<0.0001	<0.0001

NAI naloxone 0.4 mg auto-injector, NXN naloxone nasal atomization kit

^aSubject not completing the task counted as 15 min

^bWilcoxon rank-sum test performed as sensitivity analysis