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. 2015 Mar 6;4(1):39–51. doi: 10.1007/s40120-015-0026-0

Table 2.

Odds ratios of motor vehicle accidents (any) associated with exposure to use of benzodiazepines or antidepressants

Exposure Cases (74,503) Controls (744,663) Odds Ratio (95% CI)
Crude Adjusteda
Benzodiazepines
 Long-acting
  None 68,619 (92.1) 693,839 (93.2) 1.00 (reference) 1.00 (reference)
  New 87 (0.1) 807 (0.1) 1.09 (0.88–1.36) 1.03 (0.83–1.29)
  Current, not new 1,718 (2.3) 13,463 (1.8) 1.29 (1.23–1.36) 1.23 (1.16–1.29)
  Past only 4,079 (5.5) 36,554 (4.9) 1.13 (1.09–1.17) 1.07 (1.04–1.11)
 Short-acting
  None 58,630 (78.7) 597,030 (80.2) 1.00 (reference) 1.00 (reference)
  New 138 (0.2) 1,480 (0.20) 0.96 (0.80–1.14) 0.93 (0.78–1.10)
  Current, not new 5,123 (6.8) 47,502 (6.4) 1.11 (1.07–1.14) 1.05 (1.02–1.08)
  Past only 10,612 (14.2) 98,651 (13.2) 1.10 (1.08–1.13) 1.05 (1.03–1.08)
Antidepressants
 Selective serotonin reuptake inhibitors
  None 72,173 (96.9) 724,276 (97.3) 1.00 (reference) 1.00 (reference)
  New 93 (0.1) 690 (0.09) 1.35 (1.09–1.68) 1.25 (1.00–1.55)
  Current, not new 759 (1.0) 6,166 (0.8) 1.24 (1.15–1.33) 1.13 (1.04–1.22)
  Past only 1,478 (2.0) 13,531 (1.8) 1.10 (1.04–1.16) 1.00 (0.95–1.06)
 Tricyclic antidepressants
  None 72,264 (97.0) 724,937 (97.3) 1.00 (reference) 1.00 (reference)
  New 41 (0.06) 418 (0.06) 0.98 (0.71–1.36) 0.93 (0.67–1.28)
  Current, not new 552 (0.7) 4,855 (0.6) 1.14 (1.05–1.25) 1.04 (0.96–1.14)
  Past only 1,646 (2.2) 14,453 (1.9) 1.14 (1.09–1.20) 1.05 (0.99–1.10)
 Other antidepressants
  None 73,705 (98.9) 738,034 (99.1) 1.00 (reference) 1.00 (reference)
  New 28 (0.04) 233 (0.03) 1.20 (0.81–1.78) 1.10 (0.74–1.63)
  Current, not new 209 (0.3) 1,722 (0.2) 1.22 (1.05–1.41) 1.09 (0.94–1.26)
  Past only 561 (0.7) 4,674 (0.6) 1.20 (1.10–1.31) 1.07 (0.98–1.17)

Values are numbers (percentages) unless stated otherwise

aAdjusted for variables in Table 1

CI confidence interval