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. 2015 Jun 17;10(6):e0130022. doi: 10.1371/journal.pone.0130022

Fig 7. Correlation between deep-sequencing and Invader assay on the measurement of Y93H frequency.

Fig 7

Positive correlation was observed for the Y93H strain frequencies between deep-sequencing and the Invader assay of 55 HCV 1b patients (Spearman correlation r = 0.85, p < 0.001). In samples in which G allele at the preceding nucleotide position before NS5A amino acid 93 was predominant (> 85%) measured by NGS (open circle), there was a tendency to overestimate the Y93H proportion by the Invader assay.