Skip to main content
. 2015 Jun 17;10(6):e0129210. doi: 10.1371/journal.pone.0129210

Table 2. Definition of EWIs and their respective performance targets.

EWI and title Definition Numerator Denominator Target
EWI 1: On-time pill pick-up. Proportion of patients (adult or children) that pick-up ART no more than two days late at the first pick-up after the baseline pick-up. Number of patients picking-up their ART “on time” at the first drug pick-up after baseline pick-up date. Number of patients who picked-up ARV drugs on or after the designated EWI sample start date. Desirable performance (green): >90%; fair performance (amber): 80–90%; poor performance (red): <80%.
EWI 2: Retention in care. Percentage of adults and children known to be alive and on ART 12 months after initiation. Number of adults (or children) who are still alive and on ART 12 months after initiating treatment. Total number of adults or children (excluding transfers out) who initiated ART and were expected to achieve 12-month outcomes within the reporting period. Desirable performance (green): >85%; fair performance (amber): 75–85%; poor performance (red): <75%.
EWI 3: Pharmacy stock-outs. Percentage of months in a designated year in which there were no ARV drug stock-outs (both for adult and pediatric patients). Number of months in the designated year in which there were no stock-out 
days of any ARV drug routinely used at the site. 12 months of the reporting period. Desirable performance (green): 100%; poor performance (red): <100%.
EWI 4: Pharmacy dispensing practice. Percentage of patients (adults or children) being dispensed a mono- or dual-ART. Number of patients who pick up from the pharmacy, a regimen consisting of one or two ARVs. Number of patients picking up ART on or after the designated EWI sample start date Desirable performance (green) defined as 0% patients picking-up a mono- or dual-ART; poor performance (red) defined as >0% patients picking-up a mono- or dual-ART.
EWI 5: Virological suppression. Percentage of patients (adult or children) receiving ART at the site after the first 12 months of ART whose viral load is <1000 copies/ml. Number of patients receiving ART at the site after the first 12 months of ART whose viral load is <1000 copies/ml. Number of patients at the site who by national policy should have had a viral load performed 12 months after ART initiation. Desirable performance (green): >85%; fair performance (amber): 70–85%; poor performance (red): <70%.

EWI, early warning indicator

EWI4 is cross sectional in nature and is intended to assess pharmacy dispensing practices for populations on ART after any period of time on ART.