Table 2. Genome-wide significant loci and corresponding trans-ethnic results for sRAGE levels in whites and blacks.

SNP a	Gene	Chr:base pair position	Whites						Blacks
			A1 b /A2	A1 frequency	Β c	P	D’	r2 d	A1 frequency	β	P	D’e	r2 e
rs2854050	NOTCH4	6:32185605	A/G	0.06	-0.50	2.13e-11	NA	NA	0.03	-0.21	0.20301	1.0	0.003
rs2071288	AGER	6:32149260	T/C	0.005	-0.43	0.10	1.0	0.0	0.10	-0.56	2.22e-08	NA	NA
rs2070600	AGER	6:32151443	T/C	0.04	-0.67	7.26e-16	0.92	0.84	0.01	-0.63	0.017903	1.0	0.001

^aFrom dbSNP build 37

^bA1 is the minor allele in whites

^cMean change in ln(sRAGE) for Allele 1 vs. Allele 2

^dWith rs2854050 (index SNP from GWAS in whites)

^eWith rs2071288 (index SNP from GWAS in blacks)