Table 3.
Pooled diagnostic accuracy of included studies
| POD | Number of studies (n = patients) | Pooled incidence PIC (%) | Pooled AUC | Pooled CRP cutoff (range) | Pooled sensitivity (95 % CI) | Pooled specificity (95 % CI) | Pooled PPV (95 % CI) | Pooled NPV (95 % CI) | Pooled LR+ (95 % CI) | Pooled LR− (95 % CI) |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 4 (n = 546) | 18 | 0.73 | 157 (109–187) | 60 % (47–71 %) | 60 % (43–75 %) | 41 % (27–56 %) | 82 % (68–90 %) | 1.48 (0.66–2.30) | 0.67 (0.33–1.02) |
| 2 | 6 (n = 881)a | 24 | 0.72 | 190 (140–240) | 66 % (54–76 %) | 66 % (50–79 %) | 45 % (31–60 %) | 84 % (72–91 %) | 1.95 (0.87–3.03) | 0.51 (0.27–0.76) |
| 3 | 9 (n = 1567) | 32 | 0.87 | 159 (92–200) | 77 % (68–84 %) | 77 % (64–87 %) | 57 % (43–71 %) | 90 % (81–95 %) | 3.41 (1.43–5.39) | 0.29 (0.16–0.43) |
| 4 | 6 (n = 894) | 33 | 0.82 | 132 (101–180) | 80 % (71–86 %) | 80 % (67–88 %) | 60 % (45–73 %) | 91 % (83–95 %) | 3.93 (1.58–6.28) | 0.26 (0.13–0.38) |
| 5 | 6 (n = 1104)a | 17 | 0.83 | 114 (48–150) | 86 % (79–91 %) | 86 % (75–92 %) | 64 % (49–77 %) | 92 % (85–96 %) | 6.07 (2.26–9.89) | 0.17 (0.09–0.25) |
POD postoperative day, AUC area under the receiver operating curve, PPV positive predictive value, NPV negative predictive value, LR+ positive likelihood ratio, LR− negative likelihood ratio
aOne study analyzed patients in two groups, laparoscopic vs open. Patients of the two groups were included separately in the analysis (as reported in the study)