Table 2.
Correlations between levels of physical activity and scaled composite volumes of normalized brain volume measures in 39 persons with MS.
| Variable | Model 1 | Model 2 | Model 3 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| MVPA (min/day) | Light physical activity (min/day) | Sedentary behavior (min/day) | MVPA (min/day) | Light physical activity (min/day) | Sedentary behavior (min/day) | MVPA (min/day) | Light physical activity (min/day) | Sedentary behavior (min/day) | |
| NGMV (mm3) | .304 | .215 | −.099 | .297 | .167 | −.156 | .370∗ | .219 | .059 |
| NWMV (mm3) | .418∗∗ | .235 | .124 | .359∗ | .126 | −.029 | .433∗∗ | .171 | .281 |
| Hippocampus (mm3) | .325∗ | .140 | −.046 | .284 | .065 | −.151 | .499∗∗ | .018 | .164 |
| Thalamus (mm3) | .404∗ | .163 | .078 | .352∗ | .065 | −.058 | .380∗ | .024 | .228 |
| Caudate (mm3) | .418∗ | .267 | −.065 | .405∗∗ | .227 | −.123 | .539∗∗ | .198 | .099 |
| Putamen (mm3) | .341∗ | .218 | .015 | .303 | .144 | −.072 | .369∗ | .168 | .125 |
| Pallidum (mm3) | .454∗∗ | .198 | .162 | .407∗∗ | .074 | .027 | .498∗∗ | .145 | .253 |
Note: Model 1 = Pearson product-moment correlations (r); Model 2 = partial Pearson product-moment correlations (pr), controlling for days of valid accelerometer data and accelerometer wear time; Model 3 = partial Pearson product-moment correlations (pr), controlling for sex, age, clinical course of MS, and EDSS; ∗∗correlation is significant at the 0.01 level (2-tailed); ∗correlation is significant at the 0.05 level (2-tailed); MS = multiple sclerosis; MVPA = moderate-to-vigorous physical activity; NGMV = normalized gray matter volume; NWMV = normalized white matter volume.