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. 2015 Jun 18;9:162. doi: 10.3389/fnbeh.2015.00162

Figure 5.

Figure 5

Representative Western blotting of pGluR1 Ser845 from hippocampal slices of rats treated with saline or sarcosine (A) (560 mg/kg, i.p.) and after acute sarcosine (560 mg/kg, i.p.) administration with pretreatment with NBQX (10 mg/kg, i.p.) or rapamycin (20 mg/kg, i.p.) (B). Acute sarcosine treatment significantly increases the expression of pGluR1 Ser845. The increased expression of pGluR1 Ser845 resulted from acute sarcosine treatment is blocked when rats were pretreated with NBQX (B). But, the effect was not blocked by pretreatment with rapamycin (B). (*p < 0.05; **p < 0.01; ***p < 0.001 compared with saline/saline-treated group; ###p < 0.001 compared with saline/sarcosine-treated group with Tukey post hoc analysis. Values shown are mean ± SEM, n = 4 per group).