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. 2015 Jun 18;6:616. doi: 10.3389/fmicb.2015.00616

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Copyright © 2015 Prado, Bailão, Silva, de Oliveira, Marques, Silva, Silveira-Lacerda, Lima, Soares and Pereira.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Metabolic changes of P. lutzii yeast cells exposed to argentilactone. The less abundant proteins during treatment are not highlighted. The more abundant proteins are underlined. GC, glyoxylate cycle; TCA, tricarboxylic acid cycle; MCC, methylcitrate cycle; GLK, glucokinase; PFK-1, phosphofructokinase-1; PGK, phosphoglycerate kinase; ENO, enolase; PYK, pyruvate kinase; ICL, isocitrate lyase; MLS, malate synthase; MDH, malate dehydrogenase; FAH, fumarylacetoacetase; FRD, fumarate reductase; ECH: enoyl-CoA-hydratase; KAT, acetyl-CoA acetyltransferase; SDH, succinate dehydrogenase; IDH, isocitrate dehydrogenase; MCD, methylcitrate dehydrogenase.