Skip to main content
. 2015 Jun 18;6:616. doi: 10.3389/fmicb.2015.00616

Table 2.

P. lutzii less abundant proteins after incubation with argentilactone.

Functional categorya Protein description Accession numberb Protein score Fold change
METABOLISM
Amino acid metabolism Acetolactate synthase PAAG_00221 849.43 0.726
Argininosuccinate synthase PAAG_07114 6934.38 0.522
Cobalamin-independent methionine synthase MetH/D PAAG_07626 2518.10 0.577
Isovaleryl-CoA dehydrogenase, mitochondrial PAAG_04102 953.65 0.811
NADP-specific glutamate dehydrogenase PAAG_07689 1723.70 0.600
Ornithine aminotransferase PAAG_06431 1262.54 0.684
Lysine decarboxylase-like protein PAAG_03537 800.11 *
NAD-specific glutamate dehydrogenase PAAG_01002 1969.33 *
Saccharopine dehydrogenase PAAG_02693 1249.65 *
Serine hydroxymethyltransferase PAAG_07412 4659.48 0.677
Carbohydrate metabolism Mannitol-1-phosphate dehydrogenase PAAG_06473 4920.79 0.726
Eukaryotic phosphomannomutase PAAG_00889 1400.74 0.691
GDP-mannose pyrophosphorylase A PAAG_08174 860.91 *
Transketolase TktA PAAG_04444 2581.21 0.763
Coenzyme metabolism Adenosylhomocysteinase PAAG_02859 14585.17 0.440
Dihydropteroate synthase PAAG_01324 870.83 0.779
Pyridoxine biosynthesis protein pyroA PAAG_07321 2354.97 0.787
S-adenosylmethionine synthase PAAG_02901 6069.65 0.357
Nucleotide metabolism Bifunctional purine biosynthesis protein ADE17 PAAG_00731 4517.89 0.811
Adenylosuccinate lyase PAAG_04974 686.76 *
S-methyl-5-thioadenosine phosphorylase PAAG_01302 1274.52 *
UDP-N-acetylglucosamine pyrophosphorylase PAAG_06885 768.34 0.779
Phosphate metabolism Inorganic pyrophosphatase PAAG_00657 4020.00 0.771
Cell cycle and dna processing Cell division cycle protein 48 PAAG_05518 1782.70 0.719
D-tyrosyl-tRNA(Tyr) deacylase PAAG_03334 22078.91 0.741
Nascent polypeptide-associated complex subunit alpha PAAG_04571 4281.41 0.779
Peptidyl-prolyl cis-trans isomerase PAAG_06168 2417.21 0.795
Proliferating cell nuclear antigen PAAG_00923 5676.48 0.748
TCTP family protein PAAG_09083 23693.70 0.463
Thioredoxin PAAG_02364 25560.74 0.719
UV excision repair protein Rad23 PAAG_04949 1953.93 0.651
Cell rescue, defense and virulence Heat shock protein 30 PAAG_00871 6591.33 0.492
Heat shock protein 88 PAAG_07750 15855.80 0.811
Heat shock protein SSB PAAG_07775 5550.62 0.487
ENERGY
Eletron transport and membran associate energy conservation ATP synthase D chain, mitochondrial PAAG_04570 1983.65 0.748
ATP synthase gamma chain PAAG_05576 4554.87 0.595
ATP synthase subunit alpha PAAG_04820 17850.35 0.670
ATP synthase subunit beta PAAG_08037 19311.82 0.726
Glycolysis and gluconeogenesis Phosphoenolpyruvate carboxykinase AcuF PAAG_08203 2953.75 0.554
Pyruvate dehydrogenase E1 component alpha subunit PAAG_08295 904.41 0.748
Glucokinase glkA PAAG_06172 746.76 *
Phosphoglucomutase PAAG_02011 2057.00 0.482
Phosphoglycerate kinase PAAG_02869 3428.25 0.619
Pyruvate kinase PAAG_06380 9829.55 0.657
Enolase PAAG_00771 39472.25 0.779
Phosphofructokinase subunit PAAG_01583 587.46 *
Pyruvate dehydrogenase E1 component beta subunit PAAG_01534 2794.88 0.733
Glyoxylate cycle Isocitrate lyase PAAG_04549 923.71 0.827
Krebs cycle Malate dehydrogenase PAAG_00053 47991.24 0.795
Malate dehydrogenase PAAG_08449 7490.87 0.756
Isocitrate dehydrogenase subunit 1 PAAG_00856 1820.37 *
Isocitrate dehydrogenase subunit 2 PAAG_07729 1604.29 *
Succinate dehydrogenase flavoprotein subunit, mitochondrial PAAG_01725 1798.19 0.827
Oxidation of fatty acids Short-chain specific acyl-CoA dehydrogenase PAAG_05454 1028.15 *
Transport Carbonic anhydrase PAAG_05716 854.25 0.795
Clathrin light chain PAAG_08252 1049.51 0.741
GTP-binding nuclear protein ran-1 PAAG_04651 3676.19 0.527
Nipsnap family protein PAAG_05960 4593.91 0.677
Vesicular-fusion protein sec17 PAAG_06233 559.70 *
Rab GDP-dissociation inhibitor PAAG_06344 1958.40 0.625
Protein fate G-protein comlpex beta subunit CpcB PAAG_06996 2600.70 0.741
Protein disulfide-isomerase PAAG_00986 14896.18 0.670
Miscellaneous Thiol-specific antioxidant PAAG_03216 4271.92 0.427
Translation Cytosolic large ribosomal subunit protein L30 PAAG_01050 6746.86 0.756
40S ribosomal protein S0 PAAG_02111 10467.63 0.741
40S ribosomal protein S11 PAAG_06367 3129.84 0.512
40S ribosomal protein S14 PAAG_01433 1642.34 0.712
40s ribosomal protein s15 PAAG_04690 6547.01 0.625
40s ribosomal protein s26 PAAG_07847 9205.88 0.477
40S ribosomal protein S5 PAAG_05484 5524.47 0.625
40S ribosomal protein S7 PAAG_07182 7212.75 0.670
40S ribosomal protein S8 PAAG_00264 3915.07 0.651
40S ribosomal protein S9 PAAG_01435 2407.07 0.487
40S ribosomal protein S9 PAAG_03828 2402.26 0.502
60S ribosomal protein L13 PAAG_06320 5338.78 0.589
60S ribosomal protein L15 PAAG_00969 4623.56 0.468
60S ribosomal protein L18A PAAG_00952 3245.52 0.571
60S ribosomal protein L2 PAAG_00430 2292.83 0.517
60S ribosomal protein L43 PAAG_06569 12650.10 0.543
60S ribosomal protein L4-A PAAG_08888 5405.80 0.619
60S ribosomal protein L5 PAAG_00548 911.54 0.795
60S ribosomal protein L7 PAAG_06487 3961.73 0.748
60S ribosomal protein PAAG_01834 4195.17 0.538
60S ribosomal protein L31E PAAG_04965 2514.61 *
Ribosomal protein S23 PAAG_00385 923.83 *
Elongation factor 1-alpha PAAG_02024 13081.64 0.284
Elongation factor 1-beta PAAG_03028 26825.63 0.427
Elongation factor 1-gamma PAAG_03556 9096.78 0.317
Elongation factor 2 PAAG_00594 11304.17 0.403
Polyadenylate-binding protein PAAG_00244 1647.87 0.631
Ribosomal protein L19 PAAG_08497 3909.55 0.607
Ribosomal protein P0 PAAG_00801 2669.74 0.560
Ribosomal protein S20 PAAG_03322 1872.13 0.763
Ribosomal protein S6 PAAG_02634 1918.03 0.589
40S Ribosomal protein S3 PAAG_01785 6921.45 0.595
U5 small nuclear ribonucleoprotein component PAAG_07785 372.29 0.242
Unclassified Hypothetical protein PAAG_07955 2234.10 0.507
Uncharacterized protein PAAG_07989 907.76 0.657
Uncharacterized protein PAAG_04274 841.04 0.726
Uncharacterized protein PAAG_02434 1488.40 *
Uncharacterized protein PAAG_07841 11750.10 0.458
Uncharacterized protein PAAG_00724 3895.92 0.492
a

Functional category—based on the MIPS Functional categories database and GO.

b

Accession number—accession number of matched protein from Paracoccidioides database (http://www.broadinstitute.org/annotation/genome/paracoccidioides_brasiliensis/MultiHome.html).

*

Proteins detected only in control conditions.