Table II.
Univariate and multivariate logistic regression analyses of factors associated with lymph node metastasis.
| Factors | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| HR (95% CI) | P-value | HR (95% CI) | P-value | |
| Age, years (≤59/>59) | 1.078 (0.607–1.912) | 0.799 | – | NAa |
| Gender (F/M) | 1.915 (0.985–3.724) | 0.055 | 1.834 (0.921–3.655) | 0.085 |
| Tumor location (U/Md/L) | 1.178 (0.765–1.814) | 0.458 | – | NAa |
| Tumor differentiation (high/moderate/poor) | 1.337 (0.882–2.027) | 0.171 | – | NAa |
| Tumor length, cm (≤4.2/>4.2) | 1.425 (0.801–2.546) | 0.228 | – | NAa |
| pT stage (T1b-T2/T3-T4a) | 2.186 (1.087–4.398) | 0.028 | 2.186 (1.087–4.398) | 0.028 |
| resected lymph nodes, no. (≤21/>21) | 0.984 (0.554–1.747) | 0.955 | – | NAa |
| FOXF2 mRNA expression (high/low) | 1.884 (1.012–3.507) | 0.046 | 1.828 (0.975–3.430) | 0.060 |
a
Not assessed due to an insignificant result in the univariate analysis (P>0.1). F, female; M, male; U, upper; Md, middle; L, lower; HR, hazard ratio; CI, confidence interval; FOXF2, forkhead box F2.