Table III.
Univariate and multivariate Cox analyses of factors associated with cancer-specific survival.
| Factors | Univariate Cox analysis | Multivariate Cox analysis | ||
|---|---|---|---|---|
| HR (95% CI) | P-value | HR (95% CI) | P-value | |
| Age, years (≤59/>59) | 1.300 (0.872–1.936) | 0.198 | – | NAa |
| Gender (F/M) | 1.119 (0.717–1.745) | 0.621 | – | NAa |
| Tumor location (U/Md/L) | 1.131 (0.837–1.527) | 0.422 | – | NAa |
| Tumor differentiation (high/moderate/poor) | 1.352 (1.009–1.812) | 0.043 | 1.276 (0.939–1.735) | 0.119 |
| Tumor length, cm (≤4.2/>4.2) | 0.913 (0.613–1.360) | 0.654 | – | NAa |
| AJCC stage (I/II/III) | 2.384 (1.660–3.424) | <0.001 | 2.482 (1.728–3.566) | <0.001 |
| resected lymph nodes, no. (≤21/>21) | 0.646 (0.431–0.971) | 0.035 | 0.606 (0.403–0.910) | 0.016 |
| FOXF2 mRNA expression (high/low) | 1.700 (1.077–2.681) | 0.023 | 1.714 (1.085–2.708) | 0.021 |
a
Not assessed due to an insignificant result in the univariate analysis (P>0.1). F, female; M, male; U, upper; Md, middle; L, lower; HR, hazard ratio; CI, confidence interval; FOXF2, forkhead box F2; AJCC, American Joint Committee on Cancer.