Table I.
Univariate analysis of PTMC neck lymph metastasis.
| Risk factor | Lymph node cases, n | Total metastasis, n (%) | P-value |
|---|---|---|---|
| Age, years | |||
| 20–30 | 128 | 74 (57.81) | <0.001 |
| 30–44 | 761 | 272 (35.74) | |
| ≥45 | 1,095 | 299 (27.31) | |
| Gender | |||
| Male | 409 | 202 (49.39) | <0.001 |
| Female | 1,575 | 443 (28.13) | |
| Tumor size, mm | |||
| ≤5 | 630 | 211 (33.49) | 0.782 |
| >5 | 1,354 | 179 (32.78) | |
| Extrathyroidal invasion | |||
| No | 631 | 106 (16.80) | 0.510 |
| Yes | 1,353 | 539 (39.84) | |
| Single or double side tumor | |||
| Single side | 1,513 | 416 (27.50) | <0.001 |
| Double side | 471 | 229 (48.62) | |
| Subtypes | |||
| No | 1,895 | 607 (32.03) | 0.020 |
| Yes | 89 | 39 (43.82) | |
| Tumor pathological staging | |||
| pt1a | 621 | 115 (18.52) | <0.001 |
| pt3/4 | 1,363 | 529 (38.81) | |
| BRAFV600E mutation | |||
| + | 1,244 | 687 (55.23) | 0.023 |
| – | 740 | 369 (49.86) | |
| hTERT | |||
| + | 794 | 529 (66.63) | <0.001 |
| – | 1,190 | 577 (48.49) | |
| Number of primary lesion | |||
| Single | 1,182 | 284 (24.03) | <0.001 |
| Multifocality | 802 | 361 (45.01) |
PTMC, papillary thyroid microcarcinoma; hTERT, human telomerase reverse transcriptase.