Table VI.
Association between primary tumor marker expression in the epithelial component of invasive ductal breast carcinoma.
Variables | c-MYC (nuc) | mTOR | p-AKT | p53 | ER | PR | HER2 | Ki67 |
---|---|---|---|---|---|---|---|---|
c-MYC (cyt) | ||||||||
R | 0.181 | 0.158 | 0.112 | 0.084 | 0.102 | 0.144 | 0.087 | 0.064 |
P-value | 0.110 | 0.167 | 0.327 | 0.479 | 0.377 | 0.234 | 0.452 | 0.588 |
c-MYC (nuc) | ||||||||
R | 0.111 | −0.107 | 0.231 | 0.131 | 0.050 | 0.181 | 0.067 | |
P-value | 0.333 | 0.349 | 0.048 | 0.255 | 0.679 | 0.115 | 0.572 | |
mTOR | ||||||||
R | 0.134 | −0.029 | −0.029 | 0.121 | −0.018 | 0.175 | ||
P-value | 0.238 | 0.809 | 0.800 | 0.318 | 0.879 | 0.135 | ||
p-AKT | ||||||||
R | −0.041 | 0.151 | 0.058 | −0.022 | 0.053 | |||
P-value | 0.727 | 0.187 | 0.633 | 0.847 | 0.655 | |||
p53 | ||||||||
R | −0.047 | −0.077 | 0.080 | 0.235 | ||||
P-value | 0.692 | 0.536 | 0.499 | 0.045 | ||||
ER | ||||||||
R | 0.327 | −0.347 | 0.027 | |||||
P-value | 0.006 | 0.002 | 0.819 | |||||
PR | ||||||||
R | −0.251 | −0.112 | ||||||
P-value | 0.036 | 0.364 | ||||||
HER2 | ||||||||
R | 0.021 | |||||||
P-value | 0.857 |
Bold print denotes statistical significance. A negative Spearman's rank test value (R) indicates an inverse correlation. Two-sided P<0.05 was considered statistically significant. Nuc, nuclear; cyt, cytoplasmic; p-AKT, phospho-AKT; ER, estrogen receptor; PR, progesterone receptor; HER2, human epidermal growth factor receptor 2.