Table III.
Statistical evaluation of clinicopathological parameters.
| GPC6tumor/GPC6normal | ||
|---|---|---|
| Clinicopathological Median parameters | Mean ± SD | Median (min-max) |
| TNM stagea | ||
| Tumor invasionb | ||
| T1/T2 (n=6) | 1.01±0.07 | 1.02 (0.90–1.10) |
| T3/T4 (n=28) | 1.01±0.10 | 1.02 (0.55–1.18) |
| P=0.912 | ||
| Lymph node involvementb | ||
| N0 (n=11) | 1.04±0.74 | 1.04 (0.90–1.18) |
| N1/N2/N3 (n=23) | 0.99±0.10 | 1.00 (0.55–1.10) |
| P=0.08 | ||
| Distant metastasisb | ||
| M0 (n=33) | 1.01±0.09 | 1.02 (0.55–1.18) |
| M1 (n=1) | NC | |
| P=NC | ||
| H. pylori infectionb | ||
| Positive (n=17) | 1.01±0.46 | 1.01 (0.90–1.10) |
| Negative (n=13) | 1.01±0.15 | 1.05 (0.55–1.18) |
| P=0.127 | ||
| Histological gradeb | ||
| G1 (n=17) | 1.02±0.53 | 1.02 (0.90–1.10) |
| G2/G3 (n=18) | 1.01±0.13 | 1.03 (0.55–1.18) |
| P=0.644 | ||
a
TNM classification data were available for 34/35 patients.
b
Mann-Whitney U test. GPC6, glypican 6 gene; SD, standard deviation; NC, not calculated due to the large numerical discrepancy in sample sizes of M0/M1 tumors and intestinal/diffuse type tumors; H. pylori, Helicobacter pylori.