Table 2.

Scope of the enantioselective carbocyclization–borylation reaction.^[a]

Entry	Enallene	Carbocycle	Time [h]	Yield [%][b]	ee [%][c]
1			42	93	84
2			42	88	84
3			84	79	93
4			72	83	92
5			72	68	92
6			96	86	88
7			96	34	51
8			48	75	71
9			96	79	75
10			48	0	–[d]
11			86	10	68
12			48	0	–[d]
13			108	76	93

^[a] Reaction conditions: Enallene (0.2 mmol), Pd(OAc)₂ (5 mol %), 4 a (10 mol %), B₂pin₂ (1.0 equiv), and BQ (1.5 equiv) in anhydrous m-xylene (1.0 mL) under argon at 13 °C.

^[b] Yields of isolated products after column chromatography.

^[c] Determined by HPLC on a chiral stationary phase.

^[d] Not determined. E=CO₂Me, Ts=para-toluenesulfonyl.