Table I.
Characteristics of colorectal cancer cases and controls.
| Characteristics | Cases | Controls | P-valuea |
|---|---|---|---|
| N | 477 | 514 | |
| Age, yearsb | 62.34±11.86 | 62.01±11.91 | 0.661 |
| Male gender, n (%) | 276 (57.9) | 266 (51.8) | 0.054 |
| Hypertension, n (%) | 295 (61.8) | 241 (46.9) | <0.001 |
| Diabetes mellitus, n (%) | 163 (34.2) | 77 (15.0) | <0.001 |
| Homocysteineb, µmol/l | 10.41±5.61 (n=442) | 10.06±4.21 (n=508) | 0.284 |
| Folateb, ng/ml | 7.70±6.72 (n=440) | 9.25±8.33 (n=414) | 0.003 |
| Tumor size ≥5cm, n (%) | 278 (58.3) | – | |
| Lymph node invasion, n (%) | 226 (47.4) | – | |
| Tumor site, n (%) | |||
| Proximal colon | 156 (32.7) | – | |
| Distal colon | 112 (23.5) | – | |
| Mixed colon | 7 (1.5) | – | |
| Rectum | 197 (41.3) | – | |
| Unclassified | 5 (1.0) | ||
| TNM stage, n (%) | |||
| I | 49 (10.3) | – | |
| II | 200 (41.9) | – | |
| III | 191 (40.0) | – | |
| IV | 37 (7.8) | – |
a
χ2 used for categorical data, two-sided t-test used for continuous data
b
data are mean ± standard deviation. TNM, tumor-node-metastasis.