Table I.
Characteristics of TPOab-positive and -negative patients (n=318).
| Characteristics | TPOab ≤ 34 IU/ml, no. (%) (n=253) | TPOab > 34 IU/ml, no. (%) (n=65) | P-value |
|---|---|---|---|
| Age, years | 49.9±9.9 | 50.2±8.7 | 0.850 |
| fT3, pg/ml | 3.06±0.53 | 3.06±0.54 | 0.999 |
| fT4, ng/dl | 1.18±0.302 | 1.17±0.25 | 0.120 |
| TSH, µIU/ml | 2.81±2.89 | 4.48±4.9 | 0.000 |
| Nuclear grade | 0.549 | ||
| I | 30 (11.9) | 11 (16.9) | |
| II | 163 (64.4) | 39 (60.0) | |
| III | 60 (23.7) | 15 (23.1) | |
| Tumor size, cm | 0.800 | ||
| T1, ≤2 | 93 (36.8) | 25 (38.5) | |
| T2–4, >2 | 160 (63.2) | 40 (61.5) | |
| Lymph node metastasis | 0.575 | ||
| Negative | 107 (42.3) | 30 (46.2) | |
| Positive | 146 (57.7) | 35 (53.8) | |
| Metastasis | 0.018 | ||
| M0 | 233 (92.1) | 65 (100.0) | |
| M1 | 20 (7.9) | 0 | 0.0) |
| Estrogen receptor | 0.128 | ||
| Positive | 191 (75.5) | 43 (66.2) | |
| Negative | 62 (24.5) | 22 (33.8) | |
| Progesterone receptor | 0.147 | ||
| Positive | 146 (57.7) | 31 (47.7) | |
| Negative | 107 (42.3) | 34 (52.3) | |
| HER2/neu | 0.385 | ||
| Positive | 181 (71.5) | 50 (76.9) | |
| Negative | 72 (28.5) | 15 (23.1) | |
| Local recurrence-distant metastasis | 0.040 | ||
| Negative | 239 (88.5) | 64 (96.9) | |
| Positive | 14 (11.5) | 1 (3.1) |
The values are presented as mean ± standard deviation. Bold print denotes statistically significant differences. TPOab, antibodies to thyroid peroxidase; fT3, free triiodothyronine; fT4, free thyroxine; TSH, thyroid-stimulating hormone; HER2, human epidermal growth factor receptor 2.