Table 2.
Summary statistics for the samples from the second control group and cases included in this study
| Control group 2 mean (SD) | Case mean (SD) | P value (t-test, Wilcoxon rank sum or regression) | ||
|---|---|---|---|---|
| Gender | Male | 8 | 8 | |
| Female | 3 | 3 | ||
| Age at death | 76.8 (3.74) | 77.7 (4.67) | 0.620 | |
| Post-mortem delay | 33.0 (31.1) | 64.5 (24.7) | 0.012 | |
| Braak stage | 1.78 (0.44) | 1.90 (0.99) | 0.739 | |
| Temporal SVD score | 1.00 (0.00) | 1.57 (1.27) | ||
| Synaptophysin (ng/μl) | 3.95 (2.21) | 1.62 (0.63) | 0.008 | |
| Drebrin (ng/μl) | 3.87 (1.47) | 5.53 (1.13) | 0.012 | |
| SNAP-25 (ng/μl) | 0.38 (0.22) | 0.017 (0.003) | <0.001 | |
As can be seen, the cases have a significantly greater post-mortem delay. For this comparison, adjustments were used for the average NSE and total protein measurements for these two groups, which accounts for the difference in the case values between this comparison and that with the first control group.