Table 3.
Association of postoperative naming and postoperative VF fMRI activation after left ATLR in patients with and without a clinically significant naming decline
Subjects | Postoperative fMRI activation – neuropsychology score | Z-score | Corrected p-value (FWE) | Coordinates (x, y, z) in MNI space | Anatomic region |
---|---|---|---|---|---|
Left TLE with clinically significant decline | Postoperative VF activation – naming | 3.27 | p = 0.022 | 24, 6, 38 | Right MFG |
Left TLE with no significant decline | Postoperative VF activation – naming | 2.58 | p = 0.034 | −36, −20, −30 | Left HC/PHG |
Left TLE with decline > left TLE without decline | Postoperative VF activation – naming | 2.86 | p = 0.002 | 44, 12, 52 | Right MFG |
Left TLE without decline > left TLE with decline | Postoperative VF activation – naming | 3.14 | p = 0.031 | −36, 16, 6 | Left MFG |
HC, hippocampus; IFG, inferior frontal gyrus; MFG, middle frontal gyrus; MNI space, coordinates related to a standard brain defined by the Montreal Neurological Institute (MNI); PHG, parahippocampal gyrus; TLE, temporal lobe epilepsy; VF, verbal fluency.