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. 2015 Jun 18;5:10010. doi: 10.1038/srep10010

Figure 2. Five day acute cocaine exposure results in subtle but significant changes in CD4 T cell phenotype.

Figure 2

(a-c) Blood samples collected after 5 days of cocaine exposure were used for flow cytometric analysis of T cell activation markers on CD4 T cells. There were no changes on the expression of CD25, CD69 and CD38. (d) Blood samples were also tested for CCR5 expression. The data are from three mouse cohorts. Cocaine treated animals demonstrated increased levels of the receptor (Cocaine – n = 20, Non – n = 12). (e-f) Plasma from the same mice was collected and used to examine levels of Th1/Th2/Th17 cytokines (Cocaine – n = 20, Non – n = 12). For all figures, *p < 0.05, **p < 0.01, using Mann-Whitney or Kruskal-Wallis test (for 3 or more groups).