Table 3. Results from Cox Regression Model (Adjusted for Age, Sex, Disease stage, PS and the CRP/Alb ratio).
| Variables | Hazard Ratio |
95% CI |
P value | |
|---|---|---|---|---|
| LL | UL | |||
| Age (per 10 years’ increment) | 1.26 | 0.98 | 1.62 | 0.073 |
| ECOG-PS | ||||
| 0 | 1.00 | - | - | - |
| 1 | 0.94 | 0.73 | 1.22 | 0.654 |
| 2 | 3.13 | 1.94 | 5.05 | <0.001 |
| CRP/Alb ratio | ||||
| ≥0.442 | 1.00 | - | - | - |
| <0.442 | 1.34 | 1.04 | 1.73 | 0.025 |
| Disease stage | ||||
| Limited stage | 1.00 | - | - | - |
| Extensive stage | 2.13 | 1.65 | 2.76 | <0.001 |
| LDH (per 100U/L increment) | ||||
| Normal range | 1.00 | - | - | - |
| Abnormally elevated | 1.41 | 1.10 | 1.83 | 0.008 |
Abbreviations: CI, confidence interval; LL, lower limit; UL, upper limit; PS, performance status; CRP/Alb, C-reactive protein / albumin; LDH, lactate dehydrogenase.Ratio of C-Reactive Protein/Albumin is An Inflammatory Prognostic Score for Predicting Overall Survival of Patients with Small-cell Lung Cancer