Table 2. Summary of Information From Literature Review Search.

Article No.	Authors, publication date, study title, journal	Data collection procedures	Study population	Major findings
1	Benedict et al [18] 2013 Association between physical activity and brain health in older adults Neurobiol Aging	MRI imaging, self-report physical activity	331 cognitively healthy elderly > 75 years old	A positive association between level of physical activity and mini-mental state examination score, a negative association between physical activity and time to complete Trail-making B test, and the level of physical activity correlated with total brain volume and white matter volume. Physical activity is an important part of lifestyle to maintain healthy brain.
2	Geirsdottir et al [19] 2012 Physical function predicts improvement in quality of life in elderly Icelanders after 12 weeks of resistance exercise J Nutr Health Aging	Dual energy X-ray absorptiometer, TUG test and 6MW, hydraulic hand dynamometer, isokinetic dynamometer, and HRQQL questionnaire	238 participants aged ≥ 65	Changes in the 6-minute walk for distance significantly improve lean mass, muscle strength, physical function, and health related quality of life (HRQL). The improvements in physical function predict improvements in HRQL.
3	Ho et al [14] 2011 The effects of physical activity, education, and body mass index on the aging brain Hum Brain Mapp	MRI, BMI, Minnesota Leisure-Time Activities questionnaire, human brain mapping	226 with mean age of 77.9 ± 3.6 SD	Physical activity is associated with about 2-2.5% greater average white tissue volume. Increased physical activity is associated with greater average brain tissue volumes.
4	Aoyagi et al [20] 2010 Habitual physical activity in the elderly: The Nakanojo study Geriatrics & Gerontology	Physical activity questionnaire, uniaxial pedometer/accelerometer	5,000 older adults over 65 (one-tenth randomly selected to assess physical activity)	20 min/day of moderate walking along with over 60 min/day light activity leads to better physical health. A smaller amount of deliberate physical activity is associated with increased mental health.
5	Muscari et al [21] 2010 Chronic endurance exercise training prevents aging-related cognitive decline in healthy older adults: A randomized controlled study Int J Geriatr Psychiatry	3 hourly sessions/week for 12 months, baseline and post-intervention assessments of MMSE, subsub-maximal cycle ergometer test, selected anthropometric measurements, and blood drawing for laboratory determinations, PASE questionnaire	120 healthy subjects between 65 and 74 years old	Cognitive decline may be reduced with the use of endurance exercise training as assessed by the mini-mental state examination.
6	Fitzpatrick et al [22] 2007 Associations of gait speed and other measures of physical function with cognition in a healthy cohort of elderly persons J Gerontology	TICS questionnaire, 3MSE, 14 neuropsychiatric tests, anthropometric measures of height and weight, self-reports, 15-feet timed walk (regular pace and fast pace)	3,035 healthy mobile adults ≥ 75 years old	Significant association between lower modified mini mental state examination and time to walk 15 feet at rapid pace.
7	Goodpaster et al [23] 2006 The loss of skeletal muscle strength, mass, and quality in older adults: The health, aging and body composition study J Gerontology	Isokinetic dynamometry, dual-energy X-ray absorptiometry and computed tomography	3,075 men and women aged 70 - 79 years	Maintaining or gaining muscle mass does not prevent aging-associated declines in muscle strength.
8	Karinkanta et al [24] 2005 Factors predicting dynamic balance and quality of life in home-dwelling elderly women Gerontology	Rand-36 questionnaire, figure-of-eight running test, leg press dynamometer, ground reaction forces (GRF) with a force platform, a sit-to-stand and a step-on-a-stair, and simple reaction time paradigm, employing a random light or sound stimulus and a finger pushbutton as the response to the stimulus	153 women aged 70 - 78 years old	Dynamic balance is one of the most important determinants to protect independency later in life and good indicator of quality of life.
9	Rosano et al [25] 2005 Association between physical and cognitive function in healthy elderly: The health, aging and body composition study Neuroepidemiology	3MS, DSST, gait speed was measured (m/s) during two 6-m walks, both performed at usual or normal pace, NW test required the participant to walk between lines of colored tape on the floor, 20 cm apart	3,075 nondisabled men and women aged 70 - 79 years	There is a significant association between physical activity and cognitive function.
10	Brouwer et al [26] 2004 Physical function and health status among seniors with and without a fear of falling Gerontology	SF-36, ABC scale, Human Activity Profile questionnaire, limits of stability, walking speed, lower extremity muscle strength	25 older adults in fear of falling group and 25 older adults in control group	Fear of falling is associated with lower physical function.
11	van Gelder et al [27] 2004 Physical activity in relation to cognitive decline in elderly men: The FINE study Neurology	Physical activity self-report questionnaire, MMSE, and questionnaires for demographic, lifestyle and other information	295 older men	Physical activities of medium-low intensity are associated with a decrease in cognitive decline more so than activities of the lower intensity.
12	Muraki et al [9] 2001 A preliminary investigation to explore the effects of daytime physical activity patterns on health-related QOL in healthy community-dwelling elderly subjects Phys Occup Ther Geriatr	Mini-Motionlagger Actigraph, Zung Self-Rating Depression Scale, Life Satisfaction Index-Z, and Visual Analogue Scale of Happiness	69 elders	Gender is not factor, but marital status is in the difference in the correlation between physical activity and quality of life. Quality of life may differ by gender.