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. 2015 Mar 9;9(5):1651–1655. doi: 10.3892/etm.2015.2334

Table II.

Effect of lavage with the addition of 62.5 U/ml ulinastatin (MUL) to lavage fluid on amylase and lipase activity in plasma, arterial blood gases and the histological degree of pancreatitis.

Parameter Control SAP SL MUL IU
Plasma
  Amylase, U/l 1831.1 (437.6)a 10172.0 (1286.0) 5651.8 (1293.9)a 3426.8 (484.4)a 6275.1 (988.5)a
  Lipase, U/l 42.8 (21.4)a 3789.4 (496.5) 2476.9 (618.5)a 1398.8 (384.2)a 2478.5 (385.2)a
Arterial blood
  pH 7.26 (0.04)a 7.04 (0.06) 7.07 (0.06) 7.18 (0.06)a 7.05 (0.06)
  Lactic acid, mmol/l 3.40 (1.07)a 5.45 (1.04) 3.62 (0.59)a 3.33 (0.74)a 5.04 (1.01)
  Base excess, mmol/l 6.83 (1.33)a 18.99 (1.35) 17.88 (1.00)b 16.74 (1.07)a 18.61 (1.25)
Histological gradingsc
  Necrosis 0a 3 3 2a 3
  Edema 0a 3 2–3b 1a 2a
  Inflammation 0a 3 3 1–2a 1–2a
a

P<0.01

b

P<0.05 vs. the SAP group

c

calculated according to Rongione's standards. Data for plasma and arterial blood are presented as the mean (standard deviation). SAP, severe acute pancreatitis; SL, saline lavage; MUL, medium-dose ulinastatin lavage; IU, intravenous ulinastatin.