Table II.
Parameter | Control | SAP | SL | MUL | IU |
---|---|---|---|---|---|
Plasma | |||||
Amylase, U/l | 1831.1 (437.6)a | 10172.0 (1286.0) | 5651.8 (1293.9)a | 3426.8 (484.4)a | 6275.1 (988.5)a |
Lipase, U/l | 42.8 (21.4)a | 3789.4 (496.5) | 2476.9 (618.5)a | 1398.8 (384.2)a | 2478.5 (385.2)a |
Arterial blood | |||||
pH | 7.26 (0.04)a | 7.04 (0.06) | 7.07 (0.06) | 7.18 (0.06)a | 7.05 (0.06) |
Lactic acid, mmol/l | 3.40 (1.07)a | 5.45 (1.04) | 3.62 (0.59)a | 3.33 (0.74)a | 5.04 (1.01) |
Base excess, mmol/l | 6.83 (1.33)a | 18.99 (1.35) | 17.88 (1.00)b | 16.74 (1.07)a | 18.61 (1.25) |
Histological gradingsc | |||||
Necrosis | 0a | 3 | 3 | 2a | 3 |
Edema | 0a | 3 | 2–3b | 1a | 2a |
Inflammation | 0a | 3 | 3 | 1–2a | 1–2a |
P<0.01
P<0.05 vs. the SAP group
calculated according to Rongione's standards. Data for plasma and arterial blood are presented as the mean (standard deviation). SAP, severe acute pancreatitis; SL, saline lavage; MUL, medium-dose ulinastatin lavage; IU, intravenous ulinastatin.