Effects of Gs leaf extract on the levels of (A) TBARS and (B) GSH, and the enzymatic activity levels of (C) SOD, (D) CAT, (E) GPx and (F) GR in the sciatic nerves of diabetic rats. Data are expressed as the mean ± standard error of the mean (n=6) and were analyzed using one-way analysis of variance followed by the Student-Newman-Keuls post hoc test. *aP<0.05, **aP<0.01 and ***aP<0.001, vs. C group; *bP<0.05 and **bP<0.01, vs. D group. C, control group; D, diabetic group; GS50, rats received 50 mg/kg/day Gs extract; GS100, rats received 100 mg/kg/day Gs extract; TBARS, thiobarbituric acid reactive substance; GSH, glutathione; SOD, superoxide dismutase; CAT, catalase; GPx, glutathione peroxidase; GR, glutathione reductase; Gs, Gymnema sylvestre.