Figure 3.

TMP reduces the infarct volume, neurological score and brain edema during cerebral ischemia and reperfusion in rats. (A) The infarct volume of each treatment group was assayed by 2,3,5-triphenyltetrazolium chloride staining. (B) The relative infarct volume percentage was calculated with ImageJ-1.38x software (National Institutes of Health, Bethesda, MD, USA) and presented as a bar graph. (C) The neurological score of each rat was determined and recorded. (D) The water content was calculated according to the difference between the wet and dry weight, and presented as a bar graph. Data are expressed as the mean ± standard deviation, n=8. **P<0.01, *P<0.05. TMP, 2,3,5,6-tetramethylpyrazine.