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Therapeutic responses of nude mice bearing HepG2 and H1299 tumors (n = 3–5). (a) Volume (V) changes of HepG2 tumors in three groups treated with saline, doxorubicin (DOX), or aspartate-modified DOX (Asp-DOX). (b) Volumes of HepG2 tumors in different groups after 21 days of treatment. (c) Volume changes of H1299 tumors in groups treated with saline, DOX, and Asp-DOX. (d) Volumes of H1299 tumors in different groups after 21 days of treatment.
