Table I.
Parameter | Sham | Mild TAB | Severe TAB |
---|---|---|---|
Conventional measures | |||
Body weight (g) | 23.27±0.74 | 27.06±0.35 | 25.44±0.79 |
HR (bpm) | 520±7ab | 512±6a | 477±9 |
LVEDD (mm) | 3.6±0.09a | 3.67±0.17a | 4.31±0.44 |
LVESD (mm) | 2.09±0.09a | 2.05±0.23a | 3.14±0.60 |
LVWT (mm) | 1.13±0.02b | 1.46±0.03a | 1.17±0.06 |
LVEDV (µl) | 55.23±2.87a | 60.96±6.60a | 100.57±21.88 |
LVESV (µl) | 15.10±1.35a | 22.71±6.79a | 70.72±23.05 |
EF (%) | 76.15±2.71a | 73.74±4.02a | 46.18±4.79 |
FS (%) | 46.75±2.47a | 41.36±3.61a | 22.10±3.92 |
LV mass (mg) | 105.52±5.59ab | 159.04±11.30a | 198.88±12.87 |
Corrected LV mass (mg) | 84.41±4.47ab | 133.27±10.21a | 161.10±10.30 |
SV (µl) | 40.13±2.08a | 42.06±2.67a | 29.85±6.25 |
Strain measures | |||
Short axis | |||
CS (%) | −28.91±0.51a | −29.15±1.44a | −12.87±0.78 |
CSR (s−1) | −10.46±0.45a | −10.68±0.8a | −4.74±0.06 |
Long axis | |||
LS (%) | −26.83±1.8ab | −20.01±1.43a | −15.4±0.94 |
LSR (s−1) | −10.99±0.34ab | −7.8±0.41a | −5.7±0.21 |
RS (%) | 34.22±1.01ab | 26.77±0.12a | 14.28±1.08 |
RSR (s−1) | 9.95±0.62ab | 7.45±0.22a | 4.58±0.32 |
Values are presented as the mean ± standard error.
P<0.05 vs. severe TAB
P<0.05 vs. mild TAB. TAB, thoracic aortic banding; HR, heart rate; LVWT, left ventricular wall thickness; LVEDD, left ventricular end-diastolic diameter; LVESD, left ventricular end-systolic diameter; LVESV, left ventricular end-systolic volume; LVEDV, left ventricular end-diastolic volume; EF, ejection fraction; FS, fraction shortening; LV mass; left ventricular mass; SV, stroke volume; CS, circumferential strain; CSR, circumferential strain rate; LS, longitudinal strain; LSR, longitudinal strain rate; RS, radial strain; RSR, radial strain rate.