Table III.
Conventional echocardiographic parameters in the mild TAB group mice under different states of anesthesia.
| Parameter | Awake | LA | DA |
|---|---|---|---|
| Weight (g) | 27.23±0.21 | 27.06±0.35 | 26.47±0.77 |
| HR (bpm) | 563±4ab | 512±6a | 395±8 |
| LVEDD (mm) | 3.53±0.10a | 3.67±0.17a | 4.44±0.08 |
| LVESD (mm) | 1.88±0.13a | 2.05±0.23a | 3.46±0.14 |
| LVPWTd (mm) | 1.13±0.04a | 1.09±0.02a | 0.93±0.04 |
| LVPWTs (mm) | 1.67±0.06a | 1.59±0.09a | 1.12±0.07 |
| LVAWTd (mm) | 1.24±0.05a | 1.13±0.05a | 0.94±0.05 |
| LVAWTs (mm) | 1.88±0.07a | 1.74±0.08a | 1.27±0.08 |
| LVEDV (µl) | 52.85±3.48a | 60.96±6.60a | 89.70±3.75 |
| LVESV (µl) | 12.33±2.23a | 22.71±6.79a | 51.29±4.82 |
| EF (%) | 78.88±2.53a | 73.74±4.02a | 44.45±3.49 |
| FS (%) | 47.96±2.29a | 41.36±3.61a | 22.47±2.19 |
| LV mass (mg) | 172.86±9.33 | 159.04±11.30 | 175.02±7.72 |
| Corrected LV mass (mg) | 138.37±7.47 | 133.27 ±10.21 | 140.04±6.18 |
| SV (µl) | 40.53±2.06a | 42.06±2.6a | 31.41±2.01 |
Values are presented as the mean ± standard error.
P<0.05 vs. DA
P<0.05 vs. LA. TAB, thoracic aortic banding; LA, light anesthesia; DA, deep anesthesia; HR, heart rate; LVEDD, left ventricular end-diastolic diameter; LVESD, left ventricular end-systolic diameter; LVPWTd, left ventricular posterior wall thickness in diastole; LVPWTs, left ventricular posterior wall thickness in systole; LVAWTd, left ventricular anterior wall thickness in diastole; LVAWTs, left ventricular anterior wall thickness in systole; LVESV, left ventricular end-systolic volume; LVEDV, left ventricular end-diastolic volume; EF, ejection fraction; FS, fraction shortening; LV mass; left ventricular mass; SV, stroke volume.