Table IV.
Conventional echocardiographic parameters in the severe TAB group mice under different states of anesthesia.
| Parameter | Awake | LA | DA |
|---|---|---|---|
| Weight (g) | 27.16±1.27 | 25.44±0.79 | 24.35±0.47 |
| HR (bpm) | 523±5ab | 477±9a | 404±8 |
| LVEDD (mm) | 4.54±0.47 | 4.31±0.44 | 4.95±0.28 |
| LVESD (mm) | 3.60±0.61 | 3.14±0.60 | 4.09±0.43 |
| LVPWTd (mm) | 0.99±0.12 | 0.96±0.11 | 0.84±0.04 |
| LVPWTs (mm) | 1.29±0.17 | 1.40±0.17 | 1.04±0.04 |
| LVAWTd (mm) | 1.16±0.06 | 1.13±0.06 | 1.02±0.05 |
| LVAWTs (mm) | 1.46±0.11 | 1.49±0.10 | 1.32±0.11 |
| LVEDV (µl) | 101.30±23.73 | 100.57±21.88 | 103.03±14.44 |
| LVESV (µl) | 75.66±23.74 | 70.72±23.05 | 75.16±18.14 |
| EF (%) | 47.03±11.23 | 46.18±4.79 | 46.84±7.93 |
| FS (%) | 26.42±8.36 | 22.10±3.92 | 28.44±4.37 |
| LV mass (mg) | 209.36±12.13 | 198.88±12.87 | 204.42±20.13 |
| Corrected LV mass (mg) | 167.48±9.71 | 161.10±10.30 | 163.53±16.11 |
| SV (µl) | 28.64±7.55 | 29.85±6.25 | 27.87±7.16 |
Values are presented as the mean ± standard error.
P<0.05 vs. DA
P<0.05 vs. LA. TAB, thoracic aortic banding; LA, light anesthesia; DA, deep anesthesia; HR, heart rate; LVEDD, left ventricular end-diastolic diameter; LVESD, left ventricular end-systolic diameter; LVPWTs, left ventricular posterior wall thickness in systole; LVPWTd, left ventricular posterior wall thickness in diastole; LVAWTd, left ventricular anterior wall thickness in diastole; LVAWTs, left ventricular anterior wall thickness in systole; LVESV, left ventricular end-systolic volume; LVEDV, left ventricular end-diastolic volume; EF, ejection fraction; FS, fraction shortening; LV mass; left ventricular mass; SV, stroke volume.