Figure 1.

Average Tissue and Lineage Expression in Different Tumors and hPSCs

Average tissue gene expression was calculated in respect of its expression values in the original tissue. Lineage expression was calculated as the mean expression of all genes representing tissues in that lineage (n = 2 for basal cell carcinoma and choriocarcinoma; n = 5 for teratomas, medulloblastoma, liposarcoma, acute lymphoblastic leukemia, hepatocellular carcinoma, and colon cancer; n = 10 for hPSCs). Error bars represent SE. Teratomas show expression of all measured tissues and a similar expression of all lineages, while other tumors show a specific tissue and lineage expression. hPSCs show little to no expression of all the tissues. Pluripotent markers are highly expressed in hPSCs and show low to no expression in all tumors. C/PNV, central or peripheral nervous system.