Characterization of Intermediate Stages in hiPSC Reprogramming
(A) PCA classification of the human intermediate states.
(B and C) GSEA of stem cell functions (B) between distinct human intermediate stages and (C) mouse intermediate stages. Gene sets induced or repressed in the transition between two stages (−log10(FDR)) are shown by red and blue color, respectively.
(D and E) GSEA of ECC and ESC-specific genes in (D) human and (E) mouse.
See also Figure S1.