Figure 1.

The nuclear pore complex. The cytoplasmic (dark blue), central spoke (light blue), and nuclear ring (chartreuse) structures constitute the symmetric portion of the nuclear pore complex (NPC) that surrounds the central channel. The asymmetric portion of the NPC is composed of cytoplasmic filaments (purple) on the cytoplasmic side and the nuclear filaments (orange) and nuclear basket (brown) on the nuclear side of the nuclear envelope. Transmembrane and scaffold nucleoporins are found within the three symmetric ring-like structures of the NPC, and the FG-repeat containing barrier nucleoporins are depicted as filaments within the central channel.