Table 1. Summary of competitive binding results of new conjugates.
| Cys-CO-Glu | PSMA-1 | PSMA-1–IR800 | PSMA-1–Cy5.5 | |
|---|---|---|---|---|
| IC50, nmol/L | 9.93 ± 0.07 | 2.30 ± 0.06 | 1.53 ± 0.14 | 2.07 ± 0.13 |
NOTE: IC50 is the concentration required to inhibit the binding of N-[N-[(S)-1,3-dicarboxypropyl]carbamoyl]-S-[3H]-methyl-l-cysteine by 50%. Values are mean ± SD of 3 replicates.