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. 2015 Jun 12;9:3003–3016. doi: 10.2147/DDDT.S81656

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© 2015 Cui et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Decreased level of OPN secretion by DCs in CHB patients.

Notes: OPN levels were measured by ELISA in DC culture supernatant with or without HBcAg stimulation isolated from PBMC of healthy controls, and the results are presented by box plot; HC, n=20; CHB patients, n=20, ***P<0.001.

Abbreviations: OPN, osteopontin; DCs, dendritic cells; CHB, chronic hepatitis B; HBcAg, hepatitis B core antigen; PBMC, peripheral blood mononuclear cells; HC, healthy controls; ELISA, enzyme-linked immunosorbent assay.