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CLL11 serious adverse events (grade 3 or greater)
| Obinutuzumab/chlorambucil | Rituximab/chlorambucil | Chlorambucil | |
|---|---|---|---|
| Any event (%) | 70 | 55 | 50 |
| Infusion reactions (%) | 20 | 4 | 0 |
| Neutropenia (%) | 33 | 28 | 16 |
| Anemia (%) | 4 | 4 | 4 |
| Thrombocytopenia (%) | 10 | 3 | 4 |
| Leukopenia (%) | 4 | 1 | 0 |
| Infections (%) | 12 | 14 | 14 |
| Pneumonia (%) | 4 | 5 | 3 |
| Febrile neutropenia (%) | 2 | 1 | 4 |
Note: Data from Goede et al.45
Abbreviation: CLL, chronic lymphocytic leukemia.
