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. 2014 Nov 11;2:14033. doi: 10.1038/boneres.2014.33

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Copyright © 2014 Sichuan University

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/3.0/

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Nrf2 is required for normal postnatal bone acquisition. (a) Representative micro-CT images of trabecular bone structure in the distal femur of control and Nrf2^−/− mice at 8 weeks of age. (b–f) MicroCT analysis of trabecular bone structure at the distal femur in control and Nrf2^−/− mice at 3, 6, 8, 12 and 24 weeks of age (n=4–6 mice/group/age). Bone volume/tissue volume, BV/TV (%); bone area/tissue area, BA/TA (%); trabecular number, Tb. N (no./mm); trabecular thickness, Tb. Th (mm); Trabecular seperation, Tb. Sp (mm). Values shown are mean±s.e.m.